A2 Review article, literature review, systematic review

Robust nanocarriers to engineer nanobiocatalysts for bioprocessing applications

Publication Details
Authors: Bilal Muhammad, Qamar Sarmad Ahmad, Ashraf Syed Salman, Rodríguez-CoutoH Susana, Iqbal Hafiz M.N.
Publisher: Elsevier
Publication year: 2021
Language: English
Related journal or series: Advances in Colloid and Interface Science
Volume number: 293
ISSN: 0001-8686
JUFO level of this publication: 1
Open Access: Not an Open Access publication


The synergistic integration of bio-catalysis engineering with nanostructured materials, as unique multifunctionalcarrier matrices, has emerged as a new interface of nanobiocatalysis (NBC). NBC is an emerging innovation thatoffers significant considerations to expand the designing and fabrication of robust catalysts at the nanoscale withimproved catalytic characteristics for multipurpose bioprocessing applications. In addition, nanostructured ma-terials with unique structural, physical, chemical, and functional entities have manifested significant contribu-tions in mimicking the enzyme microenvironment. Afine-tuned enzyme microenvironment with an added-value of NBC offers chemo- regio- and stereo- selectivities and specificities. Furthermore, NBC is growing rapidlyand will become a powerful norm in bio-catalysis with much controlled features, such as selectivity, specificity,stability, resistivity, induce activity, reaction efficacy, multi-usability, improved mass transfer efficiency, high cat-alytic turnover, optimal yield, ease in recovery, and cost-effectiveness. Considering the above critics and uniquestructural, physicochemical, and functional attributes, herein, we present and discuss advances in NBC and itsbioprocessing applications in differentfields. Briefly, this review is focused on four parts, i.e., (1) NBC as a drivetowards applied nanobiocatalysts (as an introduction with opportunities), (2) promising nanocarriers to developnanobiocatalysts, (3) applications in thefields of biotransformation, biofuel production, carbohydrate hydrolysis,bio−/nanosensing, detergent formulations, and extraction and purification of value-added compounds, and(4) current challenges, concluding remarks, and future trends.

Last updated on 2021-24-06 at 10:05

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